Fig. 1
From: Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice
Impaired embryonic turning and neural tube closure defect upon p120ctn loss in mouse. a Breeding scheme to obtain p120ctn−/− embryos in timed matings. The table depicts numbers and percentages of p120ctn+/+, p120ctn+/− and p120ctn−/− embryos that were recovered at the developmental stages indicated (E: embryonic day). b p120ctn+/+, p120ctn+/− and p120ctn−/− littermates at E9.5. c Control (p120ctnfl/fl) and p120ctn−/− embryos were collected at different developmental stages as indicated. From E11.5 on, all p120ctn−/− embryos were resorbed. d H&E stained paraffin sections of control and p120ctn−/− E9.5 embryos. The section planes #1 to 3 are indicated in panel c as dashed lines: #1 and 2 in the E9.5 control embryo, and #3 in the p120ctn−/− embryo. Two arrows point at the posterior axis duplication in the p120ctn−/− embryo. Scale bars: 200 μm