Fig. 7From: Wingless and Archipelago, a fly E3 ubiquitin ligase and a homolog of human tumor suppressor FBW7, show an antagonistic relationship in wing developmentOverexpression of Ago increases the level of Wg in ER. Clones that overexpress Ago were generated in wing discs outlined in yellow. Endogenous intracellular Wg was detected with anti-Wg, and the clones were marked with GFP. Boxed area in (a'') and (b'') are magnified in (a''') and (b'''). a More co-localization of Wg and ER marker KDEL is observed in an Ago-expressing clone than neighboring cells (arrows). b Less co-localization of Wg and Golgi marker GM130 is seen in an Ago-expressing clone than neighboring cells (arrows). Scale bars, 5 μmBack to article page