Fig. 6

The effect of Shh on cartilage repair. a Hematoxylin & eosin staining of at 6 and 12 weeks after surgery. b Toluidine blue staining. c Immunostaining for collagen II. d ICRS Visual Histological Assessment Scale for repaired cartilage at 6 weeks. e ICRS Visual Histological Assessment Scale for repaired cartilage at 12 weeks. Significant differences between the fibrin group are indicated by * p < 0.05, **p < 0.01. Significant differences between the fibrin group are indicated by *p < 0.05 or ** p < 0.01; differences between Shh-transfected BMSC group and non-transfected BMSC group are indicated by ^# p < 0.05 or ^## p < 0.01. Scale bar: 100 μm