Fig. 6

DNA methylation changes do not necessarily correlate with changes in gene expression. For each genotype (Tet1 KO, Tet2 KO, DKO, TKO), DMRs were identified in promoters as compared to WT. The corresponding Log2 Fold change in the gene’s expression was then graphed. Because the dynamic range across the different genotypes was so different, color schemes are different for each genotype and are shown at the top of each column. Total number of DMRs used for each genotype is shown below each column