Fig. 6

Characterisation of the single and double dmrt2a and dmrt2b mutants phenotype. a, b, c Characterisation of dmrt2a^Δ100−/−, dmrt2a^Δ14−/− and dmrt2b^−/− mutant phenotype using: (a) left-sided gene spaw (20-somite stage), (b) myl7 for heart jogging at 30 hpf and (c) her7, a cycling gene (8-somite stage). d, e, f Characterisation of dmrt2a^Δ100−/−;dmrt2b^−/− and dmrt2a^Δ14−/−;dmrt2b^−/− double mutants phenotype using: (d) left-sided gene spaw (20-somite stage), (e) myl7 for heart jogging at 30 hpf and (f) myod1, a muscle differentiation marker (14-somite stage). L: left, R: right, B: bilateral, NAE: no anterior expansion, Sym: symmetric, S-Asym: slightly asymmetric, Asym: asymmetric, WT: wildtype, hpf: hours post-fertilisation