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Fig. 2 | BMC Developmental Biology

Fig. 2

From: In vivo imaging of epithelial wound healing in the cnidarian Clytia hemisphaerica demonstrates early evolution of purse string and cell crawling closure mechanisms

Fig. 2

Epithelial wounds in the Clytia medusa exumbrella heal rapidly. Two wounds were imaged at an arbitrary start time (a, d) and at the indicated times afterwards (b-c; e-f). Examples of lamellipodia are indicated with arrowheads (a, d). Experiment was replicated >10 times. g, h Closure of 6 independent wounds 50–150 mm2 in area are presented as % initial area (g) or total area (h) over time. Note that the initial area may be less than the original size of the wound, as some time inevitably elapses between wounding the animal and imaging. Area measurements were taken every 2 min. Black lines in (h) are fitted to the steepest (red) and shallowest (aqua) curves to approximate the rate of change in wound area. Scale bar = 50 μm

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