Fig. 7
From: The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis
hace1 has a role in regulating differentiation into neural ectoderm. a–c HACE1 MO (15 ng) was injected into the animal region of the right dorsal blastomere, and control MO (15 ng) was injected into that of the left dorsal blastomere at the 4-cell stage. Embryos were fixed at the stages indicated, and expression of epidermal keratin, an epidermal ectoderm marker (a), sox2, a neural ectoderm marker (b), and Xbra, a mesodermal marker (c), were analyzed by in situ hybridization. Representative images from two independent experiments are shown (lower panels)