Skip to main content
Fig. 4 | BMC Developmental Biology

Fig. 4

From: Muscleblind-like 1 is required for normal heart valve development in vivo

Fig. 4

Epithelial to Mesenchymal Transition RT2 Profiler PCR Arrays reveal few changes in gene expression in Mbnl1 E∆3/∆E3 AVC cushions at E10.5. a-c) The expression of genes involved in EMT was compared in E10.5 wild type and Mbnl1 ∆E3/∆E3 AVC endocardial cushions using the Epithelial to Mesenchymal Transition RT2 Profiler PCR Array (Qiagen). a Tgfb1, Tgfb2, and Tgfb3 transcript levels in the knockout cushions did not differ from wild type. b Clustered heat map of transcripts that showed a ≥ 2 fold change in Mbnl1 ∆E3/∆E3 cushions with P ≤ 0.05. c Transcript levels of the four genes that showed a ≥ 2 fold change in Mbnl1 ∆E3/∆E3 cushions. An asterisk indicates significant difference from wild type (P ≤ 0.05). Error bars represent 95 % confidence intervals

Back to article page