Fig. 7
From: Conservation analysis of sequences flanking the testis-determining gene Sry in 17 mammalian species
No further sequence conservation is detected in alignments of short flanking regions up to 100 kb distal to Sry. Each panel plots the probability of conservation in a multiple alignment of short sequences previously predicted by LALIGN to share pairwise similarity with the same stretch of the human sequence. Multiple alignments are generated by MUSCLE, with conservation estimated by RPhast. Values on the x-axis indicate the position relative to the human Sry ORF, with negative values 5’ of the gene, and positive values 3’ to the gene. a The SPCI is successfully rediscovered by this method, with the same two peaks of conservation as seen in Fig. 5. b, c Two representative results from the 5’ flank showing the low probability of broad conservation seen in all results other than (a). d, e Two representative results from the 3’ flank showing the low probability of broad conservation seen in all 3’ results