Figure 7
From: Generation of diverse neuronal subtypes in cloned populations of stem-like cells
Expression of region-specific genes in cultures of NE-4C neural stem cells at different stages of neural differentiation. A group of region-specific genes including pax6, gbx2, and hoxb2 was activated at the time of switching on proneural (e.g. ngn2) genes. The expression of another set of "positional" genes (dlx2, emx2, otx3) was detected in a later phase of differentiation, along with the activation of math2 neuronal gene.