Figure 4From: Identification of two novel glial-restricted cell populations in the embryonic telencephalon arising from unique originsThe putative dorsal glial restricted progenitor population can generate macroglial subtypes in mass culture. (A,C,D) Putative glial restricted progenitor cells generate GalC+ cells (A) GFAP+ cells (C) but do not generate neurons (D) after 6 days of exposure to the appropriate differentiation conditions (see Results). (B) After 4 days of growth in the pro-oligodendrocyte condition, O4+ cells were readily identifiable. (E,F) Exposure of the putative glial restricted progenitor population to BMP-4 is insufficient to result in detection of the known astrocyte marker GFAP until 10 days (E), but does induce the Astrocyte Precursor Cell marker, CD44, after 6 days (F). DAPI, blue nuclear stain (D,F). Scale bars, 100 μm.Back to article page