Figure 7
From: Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish
Nodal signals pattern the ventrolateral mesoderm along the animal-vegetal axis in a time-dependent manner. Heart myocardial cell fates were examined in embryos treated with DMSO (A1-C1), or with SB-431542 at various time points (A2-C5). (A2-C2) Embryos treated at 4 h, express small amounts of amhc and cmlc2, but not vmhc (arrows). (A3-3) cmlc2, amhc and vmhc are bilaterally expressed in embryos treated at 4.3 h. (A4-C5) All heart markers are expressed at the midline in embryos treated at 4.7 h. Images are dorsal views at 24 h, anterior to the left.