Table 3 Gene expression changes in Folr1-/- heart and conotruncal tissue-qRT-PCR
From: Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1gene activity
Gene symbol | Gene Name | Ontology | qRT-PCR | |||||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | 14-somite | 28-somite | 38-somite | |||
| Â | Â | Â | Fold change | *p value | Fold change | *p value | Fold change | *p value |
Mylpf | myosin light chain, phosphorylatable, fast skeletal muscle | cytoskeleton organization and biogenesis | -2.8 | 0.006 | --- | --- | --- | --- |
Cfl1 | cofilin 1, non-muscle | Neural crest cell migration | -1.7 | 0.002 | -1.1 | 0.3 | -1.1 | 0.24 |
Nkd2 | naked cuticle 2 homolog (Drosophila) | Wnt signaling pathway | 1.6 | 0.449 | --- | --- | --- | --- |
Cck | cholecystokinin | Cell migration | -1.9 | 0.004 | -4.5 | 0.005 | -1.7 | 0.30 |
Hand1 | Heart and neural crest derivatives expressed transcript 1 | transcription regulation, heart development, angiogenesis | 1.0 | 0.444 | +2.0 | 0.002 | -1.8 | 0.07 |
Fbln5 | Fibulin-5 | Cell-cell adhesion | --- | --- | --- | --- | -7.1 | 0.098 |
Capns1 | Calpain, small subunit 1 (Capns1) | calpain activity | --- | --- | --- | --- | +7.4 | 0.001 |
Canx | Calnexin | Protein folding | --- | --- | --- | --- | +7.6 | 0.036 |