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Figure 7 | BMC Developmental Biology

Figure 7

From: The C. elegans gene pan-1encodes novel transmembrane and cytoplasmic leucine-rich repeat proteins and promotes molting and the larva to adult transition

Figure 7

pan-1 RNAi interactions with lin-29 and let-7 . (A) lin-29 (−); pan-1(RNAi) animal with a pronounced Pvl phenotype (arrow). (B) lin-29 (−); pan-1(RNAi) animal with a smaller protruding vulva. Both animals in (A) and (B) exhibit an L3 gonadal arrest (*) and the animal in (B) is encased in unshed cuticle (arrowheads). (C) let-7(−); pan-1(RNAi) animals with an L4 arrest phenotype marked by the developmentally arrested vulva (arrow) and stunted gonad (*). (D) The percentage of animals exhibiting the “exploded out of the vulva” phenotype. The let-7 experiments were performed at 25°C as the let-7(n2853) allele is temperature-sensitive. The L4 arrest and exploded phenotype were scored at 74 hrs post-feeding. N = 126 for pan-1 RNAi and N = 98 for control RNAi. Scale bars = 10 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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