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Figure 2 | BMC Developmental Biology

Figure 2

From: The C. elegans gene pan-1encodes novel transmembrane and cytoplasmic leucine-rich repeat proteins and promotes molting and the larva to adult transition

Figure 2

pan-1 is required for larval development. (A) Graph showing the percentages of larval arrest phenotypes in pan-1 and control RNAi experiments. L4prg and L4ecd larval arrest phenotypes are differentiated by a ‘clear’ appearance and un-molted pharyngeal cuticle in the L4ecd larvae. L4prg larvae appear healthy and are viable. (B, C) Representative micrographs of time-matched pan-1 and control RNAi hermaphrodites (wild-type background). pan-1(RNAi) L4prg hermaphrodite is shown in (B). L4prg larvae are smaller than control animals (C) and sterile (no eggs generated). Scale bars = 100 μm (D) An arrested pan-1(RNAi) L3 larva encased in L2 cuticle (arrow). (E) An arrested L4prg hermaphrodite partially encased in the posterior segment of L3 cuticle (arrow). Posterior is to the right. Scale bars = 10 μm.

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BMC Developmental Biology

ISSN: 1471-213X

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