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Table 2 GO terms enriched for genes upregulated in the TE as compared to ICM a

From: Global gene expression of the inner cell mass and trophectoderm of the bovine blastocyst

GO term

Count

Percent

P value

FDRb

Biological Process

    

 Proteolysis

27

6.4

0.00

6.26

 Oxidation reduction

23

5.4

0.01

10.40

 Intracellular signaling cascade

20

4.7

0.03

43.10

 Ion transport

20

4.7

0.04

50.64

 Vesicle-mediated transport

15

3.5

0.00

5.68

 Regulation of cell proliferation

15

3.5

0.01

11.09

 Actin filament-based process

14

3.3

0.00

0.00

 Actin cytoskeleton organization

13

3.1

0.00

0.00

 Cytoskeleton organization

13

3.1

0.00

1.22

 Lipid biosynthetic process

11

2.6

0.01

12.45

 Steroid metabolic process

10

2.4

0.00

0.31

 Negative regulation of cell proliferation

10

2.4

0.00

2.24

Cell Component

    

 Plasma membrane

43

10.1

0.04

40.40

 Endoplasmic reticulum

32

7.6

0.00

0.00

 Cell fraction

16

3.8

0.00

2.50

 Cytoplasmic vesicle

14

3.3

0.03

31.04

 Vesicle

14

3.3

0.04

36.80

 Actin cytoskeleton

13

3.1

0.00

0.04

 Membrane fraction

13

3.1

0.01

11.72

 Insoluble fraction

13

3.1

0.01

15.08

 Cell projection

12

2.8

0.04

41.18

 Vacuole

11

2.6

0.00

0.87

 Endoplasmic reticulum part

11

2.6

0.00

4.14

 Apical part of cell

10

2.4

0.00

0.04

Molecular Function

    

 Ion binding

86

20.3

0.00

0.14

 Cation binding

83

19.6

0.00

0.49

 Metal ion binding

81

19.1

0.00

0.94

 Calcium ion binding

34

8.0

0.00

0.00

 Peptidase activity, acting on L-amino acid peptides

22

5.2

0.00

1.41

 Cytoskeletal protein binding

20

4.7

0.00

0.00

 Actin binding

14

3.3

0.00

0.04

 Iron ion binding

12

2.8

0.03

31.90

 Lipid binding

11

2.6

0.03

38.82

  1. a Only those GO terms which contained at least 10 differentially expressed genes are listed.
  2. b False discovery rate (x 100).