Table 1 Skull measurements in Apert syndrome mice and littermate controls

Skull length (rnsla -- rocc)¹

9.29 mm^a

9.77 mm

9.42 mm* ^a

9.83 mm

Skull height (lpto-bas)¹

4.78^a

4.65

4.91^a

4.70

Neurocranial width at squamosal bone (lpsq-rpsq)¹

6.31

6.34

6.51*

6.46

Intercanthal distance

(lflac-rflac)¹

3.67^a

3.85

3.83^a

3.95

Facial width at zygomatic process of temporal bone

(lzyt-rzyt)¹

5.81

6.00

6.04^a

6.11

Maxilla length (laalf-lptyp)¹ **

4.27^a

4.73

4.24^a

4.81

Mandible length

(mlsin-mlang)¹

4.31^a

4.53

4.47^a

4.69

Maxilla/mandible ratio

0.99

1.04

0.95

1.03

Palate length (laalf-lpns)¹ **

3.36^a

3.48

3.24^a

3.50

Length of nasal region

(lnsla-lflac)***

2.50^a

2.79

2.64^a

2.74

Overall cranial base length (amsph-bas)

3.09^a

3.19

3.25

3.28

Anterior cranial base length***

(amsph-lsyn)

1.60^a

1.68

1.68

1.69

Posterior cranial base length

(lsyn-bas)

1.66

1.70

1.78

1.77