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Table 1 Summary of analysis and results following e12.5 female genital ridge transplantation.

From: Intact fetal ovarian cord formation promotes mouse oocyte survival and development

Days of Transplantation

Analysisa

Re-Agg Gonad

Intact Gonad

In VivobControl

3

Meiosis

Zygotene-pachytene of meiosis I

Zygotene-pachytene of meiosis I

Zygotene-pachytene of meiosis I [18]

5

Ovarian Cord Formation

Ovarian cords do not form and ovary disorganized

Ovarian cords form with distinct organization of oocyte and granulosa cell clusters

Ovarian cords form with distinct organization of oocyte and granulosa cell clusters [1]

7

Oocyte Survival

Oocyte numbers significantly reduced compared to intact gonad

Oocyte numbers reduced compared to day 5

Oocyte numbers decline due to programmed breakdown [10]

12-21

Oocyte Development in Follicles

Oocytes do not survive to day 12 and follicles not observed

Oocytes survive, form follicles, and mature

Oocytes survive, form follicles, and mature [2]

  1. a For all experiments, n = 3 transplants with 4 embryos or 8 gonads per transplant
  2. b In vivo control refers to e15.5, e17.5, e19.5, and P4 - P14 stages